Retatrutide 60mg User Guide

Welcome to the club. This guide walks you through everything you need to get started: reconstituting, dosing, injecting, and storing your retatrutide. This 60mg bottle is more concentrated than the smaller bottles, so pay attention to the dosing table. Let’s get into it.

You can find this product here: GLP 3 Reta.

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SUPPLIES YOU’LL NEED

• Insulin needles — https://www.amazon.com/dp/B07P2KK5P7
• Alcohol swabs — https://www.amazon.com/dp/B07F2MQ9NJ
• Reconstitution solution (bacteriostatic water) — https://www.amazon.com/Generic-Reconstitution-Solution-Premium-Glass/dp/B0D8XMLMLN

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RECONSTITUTION (MIXING)

Each bottle contains 60mg of retatrutide in powder form. You need to add liquid to it before you can use it.

Here’s what to do:

1. Draw up 300 units of reconstitution solution (that’s 3mL, or six full insulin syringes worth, 50 units each).
2. Inject the solution slowly into the retatrutide bottle. Aim the stream at the glass wall, not directly onto the powder.
3. Swirl gently. Don’t shake it. Let it dissolve. May take a minute or two.

That’s it. You now have a more concentrated bottle where every 1 unit on the syringe = 0.2mg of retatrutide. The math is different from the 10mg, 20mg, and 30mg bottles:

Units on syringe	Retatrutide dose
2.5 units	0.50 mg
3 units	0.60 mg
5 units	1.00 mg
8 units	1.60 mg
10 units	2.00 mg
15 units	3.00 mg
20 units	4.00 mg
25 units	5.00 mg

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DOSING SCHEDULE

Start low. Your body needs time to adjust.

• Weeks 1-2: 3 units per week (about 0.60mg). This is a slightly easier-to-measure starter dose than 2.5 units.
• Week 3+: If you feel fine, move up to 5 units per week (1.00mg).
• Stay at 5 units for as long as it’s working. Months is totally fine.
• If hunger creeps back after a couple months, bump up to 8 units (1.60mg) or 10 units (2.00mg).

That’s it. Just increase gradually until you’re not getting as hungry, and you’re losing weight. Most people online and in the clinical trials say 2-4mg per week is a nice effective dose. But if 1mg works for you, why take more.

Important: this 60mg bottle is concentrated. Double-check the table before dosing. It takes fewer syringe units to get the same dose.

Stop taking it whenever you want. No tapering needed.

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HOW TO INJECT

Watch this quick video — it covers everything: https://www.youtube.com/watch?v=e9NGueNM03I

The basics:

1. Wipe the top of the retatrutide bottle with an alcohol swab.
2. Draw your dose into the syringe.
3. Pinch a bit of belly fat (or thigh), insert the needle, and push the plunger slowly.
4. Done. Once a week, same day each week if you can.

Disposal: I just bend the needle tip back and forth against the counter until it snaps off, toss the tip in the garbage, and throw the syringe away. It’s not biohazard.

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SIDE EFFECTS

Most people have none.

The most common one, when it happens, is slight nausea for the first week or two. I had that. Just a mild queasy feeling after eating a big meal. Nothing major — it goes away.

Some people get constipated early on. If you’re worried about that, take some fiber for the first couple weeks and you’ll be fine.

With retatrutide specifically, if you ramp up too quickly you might feel a bit over-stimulated — like you’ve had too much coffee. That settles down after a few weeks.

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STORAGE

Keep your bottles in the fridge — cold, dry, dark. They’ll easily last 4–6 months once reconstituted. Probably more like 8–12, but you’ll use it well before then.

Unreconstituted powder can be stored at room temperature, but the fridge is always better.